| Transactions |
| Date | Team | Player | Type | OthTm | EffDate | When |
| 5/30/2011 | KW | Cunningham | Promoted to active roster |   |   | Before |
| 5/30/2011 | KW | Rasmus | Demoted to reserve roster |   |   | Before |
| 5/30/2011 | SCS | Barney | Signed |   |   | Before |
| 5/30/2011 | SCS | Barney | Demoted to reserve roster |   |   | Before |
| 5/30/2011 | SCS | Janish | Released |   |   | Before |
| 5/30/2011 | SCS | Mijares | Released |   |   | Before |
| 5/30/2011 | SCS | Nix,L | Signed |   |   | Before |
| 5/30/2011 | SCS | Pauley | Signed |   |   | Before |
| 5/30/2011 | SCS | Scherzer | Promoted to active roster |   |   | Before |
| 5/30/2011 | SCS | Wells,R | Released |   |   | Before |
| 6/6/2011 | AAP | Berkman | Demoted to reserve roster |   |   | Before |
| 6/6/2011 | AAP | Cahill | Placed on disabled list |   | 5/31/2011 | Before |
| 6/6/2011 | AAP | Cameron | Signed |   |   | Before |
| 6/6/2011 | AAP | Cervelli | Signed |   |   | Before |
| 6/6/2011 | AAP | Cervelli | Promoted to active roster |   |   | Before |
| 6/6/2011 | AAP | Encarnacion | Released |   |   | Before |
| 6/6/2011 | AAP | Francisco,B | Signed |   |   | Before |
| 6/6/2011 | AAP | Francisco,B | Promoted to active roster |   |   | Before |
| 6/6/2011 | AAP | Jay | Released |   |   | Before |
| 6/6/2011 | AAP | Lopez,F | Released |   |   | Before |
| 6/6/2011 | AAP | Lucroy | Demoted to reserve roster |   |   | Before |
| 6/6/2011 | AAP | Nady | Released |   |   | Before |
| 6/6/2011 | AAP | Norris | Promoted to active roster |   |   | Before |
| 6/6/2011 | AAP | Stewart,I | Demoted to reserve roster |   |   | Before |
| 6/6/2011 | AAP | Thames | Signed |   |   | Before |
| 6/6/2011 | AAP | Thames | Promoted to active roster |   |   | Before |
| 6/6/2011 | SCS | Boggs,M | Promoted to active roster |   |   | Before |
| 6/6/2011 | SCS | Carmona | Released |   |   | Before |
| 6/6/2011 | SCS | Karstens | Signed |   |   | Before |
| 6/6/2011 | SCS | Karstens | Demoted to reserve roster |   |   | Before |
| 6/13/2011 | SCS | Cabrera,E | Released |   |   | Before |
| 6/13/2011 | SCS | Humber | Signed |   |   | Before |
| 6/20/2011 | HHH | Marson | Signed |   |   | Before |
| 6/20/2011 | HHH | Navarro,Y | Released |   |   | Before |
| 6/20/2011 | HHH | Wallace | Demoted to reserve roster |   |   | Before |
| 6/20/2011 | KW | Bumgarner | Promoted to active roster |   |   | Before |
| 6/20/2011 | KW | Jansen | Demoted to reserve roster |   |   | Before |
| 6/20/2011 | LC | Barmes | Demoted to reserve roster |   |   | Before |
| 6/20/2011 | LC | Castillo,E | Released |   |   | Before |
| 6/20/2011 | LC | Slaten | Signed |   |   | Before |
| 6/20/2011 | LC | Slaten | Promoted to active roster |   |   | Before |
| 6/20/2011 | SCS | Conger | Released |   |   | Before |
| 6/20/2011 | SCS | Pauley | Demoted to reserve roster |   |   | Before |
| 6/20/2011 | SCS | Sipp | Signed |   |   | Before |
| 7/4/2011 | KW | Cunningham | Demoted to reserve roster |   |   | Before |
| 7/4/2011 | KW | Gregerson | Demoted to reserve roster |   |   | Before |
| 7/4/2011 | KW | Hellickson | Promoted to active roster |   |   | Before |
| 7/4/2011 | KW | Rasmus | Promoted to active roster |   |   | Before |
| 7/17/2011 | AAP | Cahill | Activated from disabled list |   |   | Before |
| 7/17/2011 | AAP | Norris | Demoted to reserve roster |   |   | Before |
| 7/17/2011 | SCS | Coghlan | Released |   |   | Before |
| 7/17/2011 | SCS | Hernandez,Da | Signed |   |   | Before |
| 7/24/2011 | AAP | Moreland | Traded away | HMB |   | After |
| 7/24/2011 | AAP | Soriano,A | Acquired via trade | WBS |   | After |
| 7/24/2011 | AAP | Stewart,I | Traded away | HMB |   | After |
| 7/24/2011 | AAP | Victorino | Acquired via trade | HMB |   | After |
| 7/24/2011 | AAP | Zobrist | Traded away | WBS |   | After |
| 7/24/2011 | HMB | Gonzalez,Ad | Traded away | WBS |   | After |
| 7/24/2011 | HMB | Gordon | Acquired via trade | WBS |   | After |
| 7/24/2011 | HMB | Moreland | Acquired via trade | AAP |   | After |
| 7/24/2011 | HMB | Stewart,I | Acquired via trade | AAP |   | After |
| 7/24/2011 | HMB | Teixeira | Acquired via trade | WBS |   | After |
| 7/24/2011 | HMB | Victorino | Traded away | AAP |   | After |
| 7/25/2011 | AAP | Berkman | Promoted to active roster |   |   | Before |
| 7/25/2011 | AAP | Cameron | Demoted to reserve roster |   |   | Before |
| 7/25/2011 | HHH | Beachy | Promoted to active roster |   |   | Before |
| 7/25/2011 | HHH | Davis,W | Placed on disabled list |   | 7/22/2011 | Before |
| 7/25/2011 | HMB | Punto | Released |   |   | Before |
| 7/25/2011 | HMB | Stewart,I | Promoted to active roster |   |   | Before |
| 7/25/2011 | HMB | Teahen | Demoted to reserve roster |   |   | Before |
| 7/25/2011 | KW | Jones,C | Signed |   |   | Before |
| 7/25/2011 | KW | Mora | Demoted to reserve roster |   |   | Before |
| 7/25/2011 | KW | Reynolds,Mar | Released |   |   | Before |
| 7/25/2011 | WIN | Reyes,D | Promoted to active roster |   |   | Before |
| 7/25/2011 | WIN | Wheeler | Demoted to reserve roster |   |   | Before |
| 8/1/2011 | LC | Barajas | Promoted to active roster |   |   | Before |
| 8/1/2011 | LC | Beimel | Released |   |   | Before |
| 8/1/2011 | LC | Bray | Signed |   |   | Before |
| 8/1/2011 | LC | Castillo,L | Signed |   |   | Before |
| 8/1/2011 | LC | Fontenot | Released |   |   | Before |
| 8/1/2011 | LC | Galarraga | Released |   |   | Before |
| 8/1/2011 | LC | Leake | Demoted to reserve roster |   |   | Before |
| 8/1/2011 | LC | McCutchen,D | Signed |   |   | Before |
| 8/1/2011 | LC | Molina,B | Released |   |   | Before |
| 8/1/2011 | LC | Ondrusek | Signed |   |   | Before |
| 8/1/2011 | LC | Perkins | Signed |   |   | Before |
| 8/1/2011 | LC | Slaten | Released |   |   | Before |
| 8/1/2011 | LC | Smith,Joe | Signed |   |   | Before |
| 8/1/2011 | LC | Tejeda | Released |   |   | Before |
| 8/1/2011 | SCS | Castro,R | Signed |   |   | Before |
| 8/1/2011 | SCS | Kinsler | Demoted to reserve roster |   |   | Before |
| 8/1/2011 | SCS | Pauley | Promoted to active roster |   |   | Before |
| 8/1/2011 | SCS | Webb | Released |   |   | Before |
| 8/8/2011 | AAP | Cervelli | Demoted to reserve roster |   |   | Before |
| 8/8/2011 | AAP | Saltalamacchia | Promoted to active roster |   |   | Before |
| 8/8/2011 | LB | Arrieta | Promoted to active roster |   |   | Before |
| 8/8/2011 | LB | Lidge | Demoted to reserve roster |   |   | Before |
| 8/8/2011 | SCS | Garcia,J | Demoted to reserve roster |   |   | Before |
| 8/8/2011 | SCS | Gee | Signed |   |   | Before |
| 8/8/2011 | SCS | Hanigan | Released |   |   | Before |
| 8/8/2011 | SCS | Humber | Promoted to active roster |   |   | Before |
| 8/8/2011 | SCS | Scott | Released |   |   | Before |
| 8/8/2011 | SCS | Trumbo | Signed |   |   | Before |
| 8/15/2011 | HHH | Beachy | Demoted to reserve roster |   |   | Before |
| 8/15/2011 | HHH | Volquez | Promoted to active roster |   |   | Before |
| 8/15/2011 | SCS | Alvarez | Promoted to active roster |   |   | Before |
| 8/15/2011 | SCS | Youkilis | Demoted to reserve roster |   |   | Before |
| 8/15/2011 | WIN | Fuld | Promoted to active roster |   |   | Before |
| 8/15/2011 | WIN | Peavy | Demoted to reserve roster |   |   | Before |
| 8/15/2011 | WIN | Rollins | Demoted to reserve roster |   |   | Before |
| 8/15/2011 | WIN | Tomlin | Promoted to active roster |   |   | Before |
| 8/22/2011 | HHH | Davis,W | Activated from disabled list |   |   | Before |
| 8/22/2011 | HHH | Volquez | Demoted to reserve roster |   |   | Before |
| 8/22/2011 | KW | Blanco,G | Promoted to active roster |   |   | Before |
| 8/22/2011 | KW | Carroll,J | Demoted to reserve roster |   |   | Before |
| 8/22/2011 | KW | Maybin | Demoted to reserve roster |   |   | Before |
| 8/22/2011 | KW | Maybin | Promoted to active roster |   |   | Before |
| 8/22/2011 | LB | Bard,J | Demoted to reserve roster |   |   | Before |
| 8/22/2011 | LB | Hermida | Promoted to active roster |   |   | Before |
| 8/22/2011 | LB | Infante,O | Demoted to reserve roster |   |   | Before |
| 8/22/2011 | LB | Shoppach | Promoted to active roster |   |   | Before |
| 8/22/2011 | SCS | Barney | Promoted to active roster |   |   | Before |
| 8/22/2011 | SCS | Castro,R | Demoted to reserve roster |   |   | Before |
| 9/1/2011 | AAP | Cameron | Promoted to active roster |   |   | Before |
| 9/1/2011 | AAP | Cervelli | Promoted to active roster |   |   | Before |
| 9/1/2011 | AAP | Litsch | Promoted to active roster |   |   | Before |
| 9/1/2011 | AAP | Lucroy | Promoted to active roster |   |   | Before |
| 9/1/2011 | AAP | Norris | Promoted to active roster |   |   | Before |
| 9/1/2011 | AAP | Smoak | Promoted to active roster |   |   | Before |
| 9/1/2011 | HHH | Braddock | Promoted to active roster |   |   | Before |
| 9/1/2011 | HHH | Chapman | Promoted to active roster |   |   | Before |
| 9/1/2011 | HHH | Drabek | Promoted to active roster |   |   | Before |
| 9/1/2011 | HHH | Volquez | Promoted to active roster |   |   | Before |
| 9/1/2011 | HHH | Wallace | Promoted to active roster |   |   | Before |
| 9/1/2011 | HHH | Wood,Br | Promoted to active roster |   |   | Before |
| 9/1/2011 | HMB | Blanks | Promoted to active roster |   |   | Before |
| 9/1/2011 | HMB | Bourjos | Promoted to active roster |   |   | Before |
| 9/1/2011 | HMB | Byrdak | Promoted to active roster |   |   | Before |
| 9/1/2011 | HMB | Francisco,F | Demoted to reserve roster |   |   | Before |
| 9/1/2011 | HMB | Gordon | Promoted to active roster |   |   | Before |
| 9/1/2011 | HMB | Hammel | Promoted to active roster |   |   | Before |
| 9/1/2011 | HMB | Teahen | Promoted to active roster |   |   | Before |
| 9/1/2011 | HMB | Zumaya | Promoted to active roster |   |   | Before |
| 9/1/2011 | KW | Brantley | Promoted to active roster |   |   | Before |
| 9/1/2011 | KW | Cunningham | Promoted to active roster |   |   | Before |
| 9/1/2011 | KW | Gregerson | Promoted to active roster |   |   | Before |
| 9/1/2011 | KW | Hellickson | Demoted to reserve roster |   |   | Before |
| 9/1/2011 | KW | Jansen | Promoted to active roster |   |   | Before |
| 9/1/2011 | KW | Maybin | Promoted to active roster |   |   | Before |
| 9/1/2011 | KW | Mora | Promoted to active roster |   |   | Before |
| 9/1/2011 | LB | Hendrickson | Promoted to active roster |   |   | Before |
| 9/1/2011 | LB | Izturis,M | Demoted to reserve roster |   |   | Before |
| 9/1/2011 | LB | Zimmermann | Promoted to active roster |   |   | Before |
| 9/1/2011 | LC | Barmes | Promoted to active roster |   |   | Before |
| 9/1/2011 | LC | Beckett | Promoted to active roster |   |   | Before |
| 9/1/2011 | LC | Ellsbury | Promoted to active roster |   |   | Before |
| 9/1/2011 | LC | Freeman | Promoted to active roster |   |   | Before |
| 9/1/2011 | LC | Fuentes | Demoted to reserve roster |   |   | Before |
| 9/1/2011 | LC | Headley | Promoted to active roster |   |   | Before |
| 9/1/2011 | LC | Leake | Promoted to active roster |   |   | Before |
| 9/1/2011 | LC | Minor | Promoted to active roster |   |   | Before |
| 9/1/2011 | LC | Ramirez,R | Demoted to reserve roster |   |   | Before |
| 9/1/2011 | SCS | Castro,R | Promoted to active roster |   |   | Before |
| 9/1/2011 | SCS | Chamberlain | Demoted to reserve roster |   |   | Before |
| 9/1/2011 | SCS | Chamberlain | Promoted to active roster |   |   | Before |
| 9/1/2011 | SCS | Garcia,J | Promoted to active roster |   |   | Before |
| 9/1/2011 | SCS | Gee | Demoted to reserve roster |   |   | Before |
| 9/1/2011 | SCS | Hernandez,Da | Promoted to active roster |   |   | Before |
| 9/1/2011 | SCS | Karstens | Promoted to active roster |   |   | Before |
| 9/1/2011 | SCS | Kinsler | Promoted to active roster |   |   | Before |
| 9/1/2011 | SCS | Pestano | Promoted to active roster |   |   | Before |
| 9/1/2011 | WIN | Blackburn | Promoted to active roster |   |   | Before |
| 9/1/2011 | WIN | Feldman | Promoted to active roster |   |   | Before |
| 9/1/2011 | WIN | Pineiro | Demoted to reserve roster |   |   | Before |
| 9/1/2011 | WIN | Sizemore,G | Promoted to active roster |   |   | Before |
| 9/1/2011 | WIN | Walden | Promoted to active roster |   |   | Before |
| 9/8/2011 | SCS | Alvarez | Released |   |   | Before |
| 9/8/2011 | SCS | Roberts,R | Signed |   |   | Before |
| 9/15/2011 | AAP | Capps | Demoted to reserve roster |   |   | Before |
| 9/15/2011 | AAP | Saltalamacchia | Demoted to reserve roster |   |   | Before |
| 9/15/2011 | AAP | Stanton | Demoted to reserve roster |   |   | Before |
| 9/15/2011 | AAP | Torrealba | Demoted to reserve roster |   |   | Before |
| 9/15/2011 | HHH | Sanabia | Demoted to reserve roster |   |   | Before |
| 9/15/2011 | KW | League | Demoted to reserve roster |   |   | Before |
| 9/15/2011 | KW | Valverde | Demoted to reserve roster |   |   | Before |
| 9/15/2011 | LB | Soto | Demoted to reserve roster |   |   | Before |
| 9/15/2011 | LB | Tabata | Demoted to reserve roster |   |   | Before |
| 9/15/2011 | LC | Cruz,N | Demoted to reserve roster |   |   | Before |
| 9/15/2011 | SCS | Broxton | Demoted to reserve roster |   |   | Before |
| 9/15/2011 | SCS | Castro,R | Demoted to reserve roster |   |   | Before |
| 9/15/2011 | WIN | Dickey | Demoted to reserve roster |   |   | Before |
| 9/15/2011 | WIN | Durbin | Demoted to reserve roster |   |   | Before |
| 9/15/2011 | WIN | Hernandez,R | Placed on disabled list |   | 9/15/2011 | Before |
| 9/15/2011 | WIN | Street | Demoted to reserve roster |   |   | Before |
| 9/15/2011 | WIN | Zimmerman | Demoted to reserve roster |   |   | Before |
| 9/22/2011 | KW | Adams | Demoted to reserve roster |   |   | Before |
| 9/22/2011 | KW | Jansen | Demoted to reserve roster |   |   | Before |
| 9/22/2011 | LB | Oswalt | Demoted to reserve roster |   |   | Before |
| 9/28/2011 | HHH | Branyan | Demoted to reserve roster |   |   | Before |
| 9/28/2011 | HMB | Axford | Demoted to reserve roster |   |   | Before |
| 9/28/2011 | HMB | de la Rosa | Demoted to reserve roster |   |   | Before |
| 9/28/2011 | KW | Cunningham | Demoted to reserve roster |   |   | Before |
| 9/28/2011 | SCS | Gee | Promoted to active roster |   |   | Before |
| 9/28/2011 | WIN | Ellis,M | Demoted to reserve roster |   |   | Before |
| 9/28/2011 | WIN | Rios | Demoted to reserve roster |   |   | Before |